{"id":43411,"date":"2026-07-07T12:48:04","date_gmt":"2026-07-07T12:48:04","guid":{"rendered":"https:\/\/eurekainfomed.it\/dev\/?p=43411"},"modified":"2026-07-07T12:48:04","modified_gmt":"2026-07-07T12:48:04","slug":"medical-information-and-the-management-of-scientific-inquiries-from-healthcare-professionals","status":"publish","type":"post","link":"https:\/\/eurekainfomed.it\/en\/medical-information-and-the-management-of-scientific-inquiries-from-healthcare-professionals\/","title":{"rendered":"Medical Information and the management of scientific inquiries from healthcare professionals"},"content":{"rendered":"

Within the pharmaceutical industry, the Medical Information<\/strong> function serves as a key point of contact for managing scientific inquiries from healthcare professionals. Physicians, pharmacists, nurses, and researchers may contact this function to obtain clarification on clinical, pharmacological, and safety aspects related to medicinal products.<\/p>\n

Inquiries may be submitted directly to the Medical Information department by healthcare professionals or may be relayed through field-based company personnel involved in scientific and professional interactions, such as Medical Science Liaisons (MSLs) or pharmaceutical sales representatives.<\/p>\n

A fundamental and non-negotiable requirement in Medical Information activities is that inquiries must be unsolicited<\/strong>, meaning they are initiated independently by the healthcare professional and are not generated through promotional activities.<\/p>\n

Receipt and assessment of the inquiry<\/strong><\/h4>\n

The process begins with an assessment of the inquiry, focusing on its content, clinical context, and the level of detail required. At this stage, it is also essential to identify any information that may be relevant from a drug safety perspective.<\/p>\n

From an operational standpoint, the inquiry is typically recorded in a dedicated system. Key information usually includes the date of receipt, communication channel, requester\u2019s professional qualification, product and\/or therapeutic area, and the specific question raised. This initial categorization helps define priorities, identify any functions that may need to be involved, and ensure full traceability throughout the process.<\/p>\n

The inquiry is also reviewed at an early stage to identify potential pharmacovigilance-relevant information. During the interaction, a healthcare professional may mention details related to a suspected adverse reaction or other reportable situations, such as off-label use, medication errors, lack of efficacy, or exposure under special clinical circumstances. In such cases, the Medical Information Specialist forwards the relevant information to the pharmacovigilance department in accordance with company procedures and applicable regulatory requirements.<\/p>\n

Requests may involve scientific information about a medicinal product or the provision of bibliographic materials, such as full-text articles, congress abstracts, or other scientific publications. In practice, inquiries can cover a wide range of topics, including approved indications, dosing recommendations, administration methods, use in specific patient populations, efficacy and safety data, drug interactions, product stability and storage, or clarification of published studies and congress presentations. Therefore, the nature of the request must be clearly understood and properly categorized from the outset to ensure the appropriate information sources and handling process are selected.<\/p>\n

Consultation of approved sources and internal documentation<\/strong><\/h4>\n

Once the inquiry has been defined, the relevant information sources are consulted. The primary reference is the Summary of Product Characteristics (SmPC)<\/strong>, which contains the approved information regarding indications, dosage, contraindications, and safety and is intended for healthcare professionals.<\/p>\n

In addition to regulatory sources, approved standard responses, global databases, and validated scientific materials are used to ensure consistency, accuracy, and compliance in the information provided. Standard responses are pre-approved company documents developed to answer recurring scientific questions regarding specific products, therapeutic indications, or safety topics in a consistent and accurate manner. Global databases, meanwhile, contain scientific information, approved materials, previous responses, and validated content maintained at an international level, providing Medical Information Specialists with access to a shared and continuously updated knowledge base.<\/p>\n

When specific information is not readily available, the process may involve consultation with the global organization or the preparation of a local response, which is subsequently reviewed and approved at the appropriate level.<\/p>\n

Literature search and integration of evidence<\/strong><\/h4>\n

When further investigation is required, a literature search is conducted using international databases such as PubMed, Embase, Scopus, and Web of Science<\/strong> to identify relevant clinical studies, systematic reviews, and clinical guidelines.<\/p>\n

Depending on the nature of the inquiry, additional specialized resources may also be consulted, including drug interaction databases or epidemiological data sources. The collected evidence is then critically evaluated to identify the most robust and relevant information.<\/p>\n

This approach supports the development of responses that are comprehensive, scientifically sound, and aligned with the current state of knowledge.<\/p>\n

When responding requires the sharing of scientific publications, the Medical Information Specialist assesses the relevance of the requested documents and ensures that their distribution complies with copyright regulations, licensing agreements, and applicable company procedures. If distribution of the full publication is not permitted, bibliographic references or a summary of the available information may be provided, while maintaining scientific accuracy and informational value for the healthcare professional.<\/p>\n

Preparation of the response<\/strong><\/h4>\n

After integrating the available information, the Medical Information Specialist prepares a response that is clear, accurate, and supported by scientific evidence while avoiding interpretations that are not justified by the data.<\/p>\n

The use of appropriate disclaimers is a critical component of scientific communication because it helps properly contextualize the information and ensures that it is used in accordance with scientific and regulatory requirements. The response should also make clear that it does not constitute medical advice but rather a summary of the available evidence. Responsibility for clinical and therapeutic decisions remains with the healthcare professional.<\/p>\n

Conclusions<\/strong><\/h4>\n

The management of scientific inquiries within Medical Information requires a structured process, multidisciplinary expertise, and constant attention to regulatory compliance.<\/p>\n

A rigorous approach enables organizations to provide reliable, consistent, and compliant responses, supporting healthcare professionals in accessing up-to-date scientific information while contributing to the safe and appropriate use of medicinal products.<\/p>\n

References<\/p>\n

    \n
  1. European Medicines Agency (EMA) \u2013 Good Pharmacovigilance Practices (GVP)<\/em><\/li>\n
  2. Italian Medicines Agency (AIFA) \u2013 Pharmacovigilance<\/em><\/li>\n
  3. European Medicines Agency (EMA) \u2013 Product Information Requirements<\/em><\/li>\n
  4. European Medicines Agency (EMA) \u2013 How to Prepare and Review a Summary of Product Characteristics (SmPC)<\/em><\/li>\n
  5. PubMed \u2013 National Library of Medicine, biomedical literature database<\/li>\n
  6. Embase \u2013 Elsevier biomedical research database<\/li>\n
  7. International Council for Harmonisation (ICH) \u2013 ICH Guidelines<\/em><\/li>\n
  8. European Medicines Agency (EMA) \u2013 ICH E2E Pharmacovigilance Planning<\/em><\/li>\n<\/ol>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    Within the pharmaceutical industry, the Medical Information function serves as a key point of contact for managing scientific inquiries from healthcare professionals. 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